BANNER INTERNO

Speakers


PLENARY LECTURES

Carmen Galán

School of Chemistry, Cantock's Close, University of Bristol, UK

Lecture Title:
Synthetic glyco-tools for exploring and exploiting the glycome

  • BIOSKETCH
    M. Carmen Galan is a Professor of Organic and Biological Chemistry in the School of Chemistry at the University of Bristol. In 2017, she was awarded the RSC Dextra Carbohydrate Chemistry award in recognition of her research into new synthetic methodologies for oligosaccharide synthesis and the development of novel glycoconjugate probes and in 2021 she received the RSC Jeremy Knowles award for the development of bioinspired synthetic probes for the targeting and regulation of cellular processes in mammalian and plant cells. In 2022 she received the “Merit Award” granted by the Society of Spanish Scientists in the United Kingdom (SRUK/CERU).

    Prior to that, she held an ERC consolidator award (2015-2020), EPSRC Career Acceleration fellowship (2012-2017) and a Royal Society Dorothy Hodgkin Fellowship (2008-2012), which followed a lectureship in the same department (from 2006). Carmen received her Ph.D. in Organic Chemistry from the Complex Carbohydrate Research Center at The University of Georgia, USA, under the supervision of Prof. Geert-Jan Boons. She then moved to California to pursue post-doctoral research with Prof. Chi-Huey Wong at The Scripps Research Institute. After that, she continued her post-doctoral training at M.I.T with Prof. Sarah O'Connor before moving to the UK
Nathalie Juge

Quadram Institute Bioscience, Norwich, UK

Lecture Title:
Glycobiology of host-microbe interactions in the gut

  • BIOSKETCH
    Nathalie Juge is a Group Leader at the Quadram Institute Bioscience (QIB) in Norwich (UK), Deputy Lead of the Gut Microbes and Health Institute Strategic Programme, QIB Deputy Scientific Chief Officer and honorary Professor at the University of East Anglia (Norwich). Prof Juge’s background is in the molecular studies of protein-glycan recognition in relation to gut glycobiology, gut microbiology and nutrition. She did her PhD at Marseille University (Faculty of Sciences) in 1993 and subsequent post-docs at the Carlberg Research Institute (Copenhagen) and Institute of Food Research (Norwich) on the structure-function relationships of carbohydrate-active enzymes and inhibitors.  She was a lecturer at Marseille University since 1999 before joining QIB in 2008 as a group leader to develop a research programme on the role of mucus in the interaction between the gut microbiota and the host.  Her Lab currently focuses on the role of host (mucin), microbial and dietary glycans in the mechanisms of adaptation of commensal bacteria to the gut and communication to the host. The team uses multidisciplinary approaches covering molecular microbiology, biochemistry, glycomics, functional genomics and cell biology, including the use of in vitro organ cultures and organoids and mouse models.
Salomé Pinho

Institute for Research and Innovation in Health (i3S), University of Porto, PT

Lecture Title:
A bitter-sweet symphony in Immunity: glycans as key immune-checkpoints at the frontiers of inflammation, autoimmunity and cancer.

  • BIOSKETCH
    Salomé Pinho developed her PhD research on Cancer Glycobiology at the Institute of Molecular Pathology and Immunology of Univ. Porto (IPATIMUP) and at Boston Medical School, MA, USA from 2006 to 2009. She performed her postdoctoral work at University of Porto exploring the role of glycans in chronic inflammation and cancer. At present, she is Principal Investigator at the Institute for Research and Innovation in Health (i3S) at University of Porto and Professor at Faculty of Medicine of University of Porto, Portugal. Her research activity is focused on the understanding of the role of post-translational modifications by glycosylation in the regulation of key proteins´ functions involved in cancer, chronic inflammation and autoimmunity, envisioning potential clinical applications. She is author of several publications in international peer-reviewed journals (as first and senior author) including Nature Reviews Cancer, Oncogene, PNAS, Gastroenterology, Arthritis & Rheumatology; Cancer Immunology Research among others. She coordinates a multidisciplinary research group (Immunology, Cancer & GlycoMedicine) at i3S composed by Post-Docs, PhD students, Master students, young researchers and clinical researchers. She is the Principal Investigator of several national/international funded projects in the field of glycobiology, cancer and inflammation, including the coordination of European (Horizon Europe) grants on glycobiology being recently awarded with an ERC Synergy grant. She has been granted with several prizes including the Young Investigator Award from the European Association for Cancer Research; the Glycobiology Significant Achievements award in 2020 by the American Society of Glycobiology and the Pfizer Award for Clinical Research in 2021.

INVITED LECTURES

Ana Arda

Ikerbasque associate principal investigator, CICbioGUNE, Derio, ES

Lecture Title:
Molecular recognition of glycans by lectins: new tools and important features

  • BIOSKETCH
    AA studied Chemistry at University of A Coruña (Spain), from where she got her PhD degree in the field of Natural Products Chemistry in 2006. After that, she moved to The Netherlands to join the Bioorganic chemistry group of Prof H. Kamerling at the Bijvoet Center for Biological Research (Utrecht), focused on glycan chemistry. She then moved to Madrid, to the Center for Biological Research (CIB-CSIC) to join the group of Prof. Jiménez-Barbero, where she learnt about NMR tools and strategies to understand and characterize glycan structural features and their molecular recognition processes by protein receptors. In 2014, she moved with the group of Prof. Jiménez-Barbero to CIC bioGUNE Research Center in Bilbao (Spain). In 2015 she was awarded with the tenure-track-like Ramón y Cajal Fellow, and in 2022 she was promoted to Ikerbasque Research Associate. At CIC bioGUNE she is involved in different projects where, by employing a combination of different chemical, biophysical and biomolecular techniques and through different collaborations, she tries to understand from a molecular perspective, how glycans bind to special protein receptors, mainly lectins and antibodies, in biologically relevant processes, mostly related to host-pathogen interactions and immune response.
Ángeles Canales

Universidad Complutense de Madrid, ES

Lecture Title:
New NMR methods for studying complex N-glycans and glycoproteins.

  • BIOSKETCH
    Angeles Canales studied chemistry at Autónoma University of Madrid and received his Ph. D. in 2005 under the guidance of Prof. Jesús Jiménez Barbero. In 2006 she joined the pharmaceutical company ROVI S.A. where she worked in the Research and Development Department for three  years. In 2009, she moved back to academia as “Ramón y Cajal researcher” working at Complutense University of Madrid. In 2015 she obtained an assistant professor position at Complutense University and in January 2022 she was promoted  to associate professor in the same University. Her research is focused on the study of molecular recognition processes by using NMR spectroscopy and in the development of new NMR methodologies to study complex molecules by using paramagnetic metals.
Francisco Corzana

Universidad de La Rioja, ES

Lecture Title:
Structure-based design of glycopeptides with applications in cancer therapy and diagnosis

  • BIOSKETCH
    Dr. Francisco Corzana obtained his PhD in Chemistry from the University of La Rioja in 2001 with the aim of synthesizing enantiomers of quaternary amino acids. He then completed two postdoctoral research positions. The first was at the University of Copenhagen with Professor Engelsen, where he studied the conformational behavior of starch-derived carbohydrates using molecular dynamics simulations. The second was at the Institute of General Organic Chemistry (CSIC) in Madrid, under the supervision of Professors Jesús Jiménez Barbero and Juan Luis Asensio. During this postdoc, he synthesized modified aminoglycoside antibiotics and analyzed their conformation in solution using a combination of NMR experiments and MD simulations.

    In 2005, Dr. Corzana returned to the University of La Rioja as a "Ramon y Cajal" researcher and now holds a permanent position as associate professor. His research focuses on the synthesis and structure of glycopeptides and their use in clinical applications such as the development of therapeutic vaccines for cancer treatment and early tumor detection. His work has led to the development of several cancer vaccines that have been shown to be effective in mice.

    Dr. Corzana is the principal investigator of the DIRNANO Curie ITN (H2020-MSCA-ITN2020) project at the University of La Rioja (reference: 956544). The main objective of this project is to study the interactions of biocompatible nanomaterials with the innate immune system at the molecular level. He was also the principal investigator of the ProteinCojungates project (MSCA-ITN -2015-ETN, reference: 675007) at the University of La Rioja, which aimed to develop a new generation of antibody-drug conjugates for the targeted treatment of tumors. Dr. Corzana's diverse research background has been further enhanced by several research stays at renowned universities and research groups. He has completed three short stays, including one in 2012 at the University of Oxford with Professor Ben Davis to synthesize antifreeze-like glycopeptides, and two stays at the University of Cambridge in 2014 and 2016 with Dr. Bernardes to work on selective chemical modification of proteins.

    Dr. Corzana has published more than 150 articles in top-tier journals and has given more than 20 invited talks at national and international conferences. He is currently a visiting professor at the University of Cambridge.
Ramon Hurtado

Institute of Biocomputation and Physics of Complex Systems, University of Zaragoza, ES, / Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen, DK

Lecture Title:
Mechanisms of glycosyltransferases: different strategies to achieve glycosylation

  • BIOSKETCH
    Ramón Hurtado-Guerrero studied Pharmacy at the University of Granada (Spain). He obtained his Ph.D. in 2001. After postdoctoral work at University of Leeds with Prof. Mike McPherson, UCL (UK) with Prof. Vallance and the University of Dundee with Prof. van Aalten, he started his academic career in 2009 at the University of Zaragoza as a senior ARAID researcher. He is also a visiting researcher at University of Copenhagen since 2018. His research interests include structural Glycobiology to elucidate the role of glycans in protein recognition and catalysis. 
Luis Izquierdo

Barcelona Institute for Global Health (ISGlobal), Hospital Clínic—University of Barcelona, Spain /  CIBER de Enfermedades Infecciosas, Barcelona, ES

Lecture Title:
Essential glycosylation pathways in Plasmodium falciparum

  • BIOSKETCH
    He obtained his PhD degree studying the lipopolysaccharide of Klebsiella pneumoniae, associated with hospital outbreaks and severe community-acquired infections. During his postdoctoral training, funded by Marie Curie and EMBO Fellowships, in the School of Life Sciences (University of Dundee, Scotland), he studied the glycobiology of protozoan parasites that cause neglected tropical diseases. He focused on Trypanosoma brucei that produces African sleeping sickness, with the aim to uncover novel parasitic processes amenable for therapeutic intervention. He moved to ISGlobal, obtaining in 2010 a Ramón y Cajal contract to study the glycobiology of the malaria parasite, as a way to discover novel ways to disrupt parasite growth and to characterize new antigens for diagnosis or vaccination. His laboratory research expertise is in the areas of biochemistry and glycobiology, functional genomics of carbohydrate-active enzymes and molecular parasitology. 
Carmen Ortiz-Mellet

University of Seville, ES

Lecture Title:
Broadening the glycomimetic landscape: targeting glycosidases, immune receptors and lectins.

  • BIOSKETCH
    She studied Chemistry at the University of Seville, where she received her doctorate in 1984 in the field of glycoconjugate synthesis, and pursued postdoctoral training at the Center for Nuclear Studies in Grenoble, France, where she acquired skills in supramolecular chemistry and synthesis of bioactive complex oligosaccharides. Upon her return to the University of Seville, she assumed the direction of the Group of Bioorganic Chemistry of Carbohydrates, being promoted to Full Professor of Organic Chemistry in 2009. Since 2019 she serves as Director of the Department of Organic Chemistry of the Faculty of Chemistry of the University of Seville, and as Coordinator of the Science Section in the Research Commission. She has been Visiting Professor at the École Normale Supérieure de Cachan (Paris-Saclay University), at the University of Picardie in France and at the University of Hokkaido in Japan. Her field of work and the research lines of her group revolve around the general theme "Carbohydrates for health and well-being" with a clear focus on the development of new therapies, both for orphan diseases and global health problems. The ongoing projects centre in the application of the “chemical mimic” concept to the design of glycoconjugate mimetics as drug candidates or diagnostic probes for metabolic diseases (lysosomal storage disorders), age-related diseases (Alzheimer disease), cancer (tumor-associated carbohydrate mimetics) and immunomodulation (adjuvants, lectin ligands and anti-inflammatory compounds). She has been awarded the “Premio Fama” for her research career and the “Knowledge Transfer Award” of the University of Seville in the area of Natural Sciences.
Benjamin Schumann

Francis Crick Institute and Imperial College London, London, UK

Lecture Title:
Chemical Precision Tools to Explore the Surprising Biology of SARS-CoV-2 O-Glycosylation

  • BIOSKETCH
    Ben is a chemical biologist with a profound interest in investigating the biology of glycans. After completing his biochemistry undergraduate studies in Tübingen, Germany, he was trained in synthetic carbohydrate chemistry in the lab of Peter H. Seeberger at the Max Planck Institute of Colloids and Interfaces Potsdam and the FU Berlin. Developing vaccines against pathogenic bacteria based on synthetic glycans, Ben learnt to apply his compounds in biological settings in vivo and in vitro. For his achievements, he received the Award for Excellence in Glycosciences and, in 2017, the prestigious Otto Hahn Medal by the Max Planck Society. During his postdoctoral work in the lab of Carolyn R. Bertozzi at Stanford University as an Alexander von Humboldt foundation Feodor Lynen fellow, Ben developed an interest for “Precision Tools” to study glycosylation of human cells in great detail. He started as a Group Leader at the Francis Crick Institute and Imperial College London in 2018 to develop such tools, using a combination of organic and chemo-enzymatic synthesis, molecular and cell biology. His group routinely incorporates cutting-edge methods of metabolic and protein engineering as well as chemical glycoproteomics. The group was part of a large team that has been awarded the 2021 RSC Horizon Prize in Chemical Biology. Ben is an EMBO Young Investigator, has received an Imperial College Outstanding Early Career Researcher Award and recently an ERC Starting Grant.
 María Pía Lenza

Award for the best thesis 2021, Grupo Especializado de Hidratos de Carbono, RSEQ; University of Naples Federico II,  Napoli, IT

Lecture Title:
Deciphering the recognition features of glycans by human lectins at the molecular level.

  • BIOSKETCH
    M. Pia Lenza has got her bachelor degree in Biotechnology and master degree in Medical Biotechnology at University of Naples “Federico II”. After, she attended the residency program in pathology and clinical biochemistry at University of Naples Federico II- Faculty of Medicine. In July 2018 she started the PhD in CICbioGUNE in the Chemical Glycobiology Laboratory under the supervision of Jesús Jímenez-Barbero and June Ereño Orbea. Here she studied the glycan recognition using NMR spectroscopy and X-Ray Crystallography. She received her PhD in Molecular Biology and Biomedicine in 2021, and she joined a post-doc position in the same laboratory, studying the interaction between glycans and lectins. In particular, she focused her attentions on the interaction between Siglecs and glycomimetics and/or Antibodies. In October 2022, she moved to University of Naples Federicoo II, in Chemical Science Department, under the supervision of Proff. Antonio Molinaro, Alba Silipo and Roberta Marchetti as a Research Fellow.

Important Dates


  • Opens REGISTRATION and ABSTRACTS submission
    9/1/2023
  • Early REGISTRATION
    Deadline ABSTRACTS submission for Oral Communications

    27/2/2023
  • Late REGISTRATION
    Deadline ABSTRACTS submission for Poster Communications

    13/3/2023
  • XIII Carbohydrate Meeting
    27-29/3/2023

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